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Pets With A Rare Illness Can Help Design Vaccines For Humans
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Story By: Larry Stine



  Originally Published on: 3/8/2014

Imagine using pets to find a cure for cancer or any other disease. That's what researchers and doctors are doing at Penn Vet in Philadelphia. By treating pets with new drugs and vaccines, they can use the information to design more effective treatments for humans. Here's Carl Azuz with today's Health Minute. Aspen has osteosarcoma, a bone cancer, that up till now, had a very poor outcome for patients. Despite limb amputation and chemotherapy, 60 percent of dogs with osteosarcoma died within 10 months of diagnosis. But Apsen is lucky. His owners have volunteered him to be a part of a bone-cancer vaccine study at Penn Vet. It has shown great promise in attacking the aggressive tumor. "We've been able to demonstrate that it is effective in preventing osteosarcoma from coming back," says Dr. Nicola Mason of the University of Pennsylvania School of Veterinary Medicine. Results have been impressive. In the first five furry patients who were vaccinated over a year ago, four are still alive and tumor free. And there have been no complications. "So far, we've found that the vaccine appears to be very safe," says Dr. Mason. And what's even more interesting, the vaccine was not originally designed for animals. "It was designed for humans, in fact the gene we were targeting was expressed in human breast cancer," says Dr. Mason. But the genes were similar to canine osteosarcoma. So Dr. Mason asked to test the vaccine on dogs first. By looking at the canine data, researchers hope to design a safe vaccine not only for dogs, but one that can help children with osteosarcoma and adults with deadly tumors, including advanced breast cancer.

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